From routine cell culture in the academic lab to process-development workflows in regenerative medicine, our HPL is trusted across a broad range of human-cell applications.
Bone-marrow-, adipose-, umbilical-cord- and Wharton's-jelly-derived mesenchymal stromal cells consistently show accelerated proliferation in HPL while retaining their surface-marker phenotype and differentiation potential.
Fibroblasts, endothelial cells, keratinocytes, and other adherent primary cells benefit from the human-derived growth factor cocktail found in HPL.
Support preclinical studies in orthopedics, wound healing, and tissue engineering with a human-relevant cell-culture environment.
Culture donor cells in HPL-containing medium to produce exosomes and extracellular vesicles under xeno-free conditions.
Use Regencore HPL in early-passage expansion to build well-characterized research cell banks with consistent phenotype.
Evaluate scale-up strategies, media optimization, and bioreactor workflows with a reproducible, defined supplement.
Researchers increasingly adopt HPL over fetal bovine serum for its human origin, growth-factor richness, and reproducibility.
| Attribute | Regencore HPL | Fetal Bovine Serum (FBS) |
|---|---|---|
| Origin | Human (pooled platelets) | Bovine (animal origin) |
| Xeno-Free | Yes | No |
| MSC Proliferation | Typically faster; higher population doublings | Slower; variable by lot |
| Lot-to-Lot Variability | Low (large-pool formulation) | High |
| Translational Suitability | Human-relevant; no animal components | Animal-derived; regulatory concerns |
| Supply Risk | Stable, US donor base | Subject to global shortages |
Our scientific team can help you optimize your HPL-based culture for your cell type and workflow.
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